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Tricia Serio, Ph.D.

Assistant Professor of Molecular and Cellular Biology Biochemistry

Professor Serio's research focuses on self-perpetuating protein conformations in the yeast Saccharomyces cerevisiae as a model for severe neurodegenerative diseases in mammals. In a variety of systems, proteins have been linked to processes historically limited to nucleic acids, such as infectivity and inheritance. Such proteins, termed prions, adopt multiple physical and therefore functional states in vivo, an attribute underlying their atypical roles in the cell. Professor SerioÆs current work seeks to elucidate the molecular mechanisms that module prion protein conformational flexibility in vivo using the yeast Saccharomyces cerevisiae as an experimental model.

Ph.D. Yale University, 1997
Molecular Biology

M.Phil. Yale University, 1995
Molecular Biology

B.S. Lehigh University, 1991
Molecular Biology

For more information, please see http://research.brown.edu/myresearch/Tricia_Serio