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Susan Gerbi, Ph.D.

George Eggleston Professor of Biochemistry
Chair, Department of Molecular Biology, Cell Biology and Biochemistry

Professor Gerbi is currently working on two major research projects. The first involves the initiation of DNA replication. Her lab has devised a method to map the start site of DNA replication at the nucleotide level. Her research in progress suggests that a steroid hormone receptor may play a direct role for initiation of DNA replication. Professor GerbiÆs second project focuses on ribosome structure, evolution, and biogenesis. Studies in the Gerbi lab demonstrated that certain sequences are evolutionarily conserved, even between bacteria and higher organisms, thus pinpointing regions of functional importance in ribosomal RNA (rRNA). Her lab was the first to show that small nucleolar RNA is required for rRNA processing. Their recent investigations open the possibility for a new class of antibiotics targeted against eukaryotic pathogens.

Ph.D. Yale University, 1970
Biology

M. Phil. Yale University, 1968
Biology

B.A. Barnard College, 1965
Zoology

For more information, please see http://research.brown.edu/myresearch/Susan_Gerbi